Oral cancer prevention advances with a translational trial of green tea.
نویسنده
چکیده
This perspective on Tsao et al. (beginning on p. 931 in this issue of the journal) discusses green tea extract, which was shown for the first time to have dose-dependent effects in a clinical chemopreventive setting (oral premalignant lesions). This translational trial provides important data on angiogenesis and other biomarkers on which to base future clinical research, which should include trials of green tea extract or polyphenols combined with other natural or synthetic compounds to enhance chemopreventive effects.
منابع مشابه
Cancer prevention by green tea: evidence from epidemiologic studies.
In contrast to the consistent results of an inhibitory effect of green tea extracts and tea polyphenols on the development and growth of carcinogen-induced tumors in experimental animal models, results from human studies are mixed. Both observational and intervention studies have provided evidence in support of a protective role of green tea intake in the development of oral-digestive tract can...
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Objectives Oxidative stress consequent to cigarette smoking may alter the salivary antioxidant defense system and lead to oral cancer. Green tea, with antioxidant properties, interacts with saliva upon entering the mouth. This experimental study explored the preventive effect of green tea on cigarette smoke-induced oxidative damage over 3 weeks. Methods In this clinical trial study sixty volun...
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Background and Aim: Breast cancer is one of the most common types of cancers and is the second leading cause of death form of cancer in women. In recent years, many scientific and medical studies have shown that Green tea has anti-proliferative, anti-mutagenic, anti-oxidant, antibacterial and antiviral effects. Some Green tea polyphenols have anti-cancer activity. In the present study, the effe...
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BACKGROUND AND AIM: In a normal non-diseased person, the throat condition is favorable for the growth of different germs. This investigation intended to assess the impression of mouthwash obtained from green tea and chlorhexidine on the oral sanitation in intubated subjects in the intensive care unit (ICU). METHODS: In th...
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ورودعنوان ژورنال:
- Cancer prevention research
دوره 2 11 شماره
صفحات -
تاریخ انتشار 2009